3-(4-Boc-1-piperazinyl)benzoic Acid

3-(4-Boc-1-piperazinyl)benzoic Acid - Names and Identifiers

Name	3-[4-(tertbutoxycarbonyl)piperazin-1-yl]benzoic acid
Synonyms	3-(4-Boc-1-piperazinyl)benzoic Acid 3-(4-Boc-piperazin-1-yl)benzoic acid 1-Boc-4-(3-carboxyphenyl)-piperazine 1-(3-carboxyphenyl)-4-Boc piperazine 3-[4-(tertbutoxycarbonyl)piperazin-1-yl]benzoic acid tert-Butyl 4-(3-carboxyphenyl)piperazine-1-carboxylate 4-(3-carboxyphenyl)-1-Piperazinecarboxylic acid 1-(1,1-dimethylethyl)ester 1-Piperazinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl) ester
CAS	193818-13-2
InChI	InChI=1/C16H22N2O4/c1-16(2,3)22-15(21)18-9-7-17(8-10-18)13-6-4-5-12(11-13)14(19)20/h4-6,11H,7-10H2,1-3H3,(H,19,20)

3-(4-Boc-1-piperazinyl)benzoic Acid - Physico-chemical Properties

Molecular Formula	C16H22N2O4
Molar Mass	306.36
Density	1.213±0.06 g/cm3(Predicted)
Boling Point	482.0±40.0 °C(Predicted)
pKa	4.47±0.10(Predicted)
Storage Condition	2-8℃
Refractive Index	1.561

3-(4-Boc-1-piperazinyl)benzoic Acid - Introduction

3-[4-(tertbutoxycarbonyl)piperazin-1-yl]benzoic acid is an organic compound whose chemical name is 3-(tert-butoxycarbonyl)piperazin-1-yl)benzoic acid, often referred to as Boc-piperazine carboxylic acid.

Properties: 3-[4-(tertbutoxycarbonyl)piperazin-1-yl]benzoic acid is a solid powder, white or white-like crystal, with good solubility. The relative molecular mass of the compound is 311.37g/mol, and its chemical structure contains a piperazine ring and a benzoic acid group that are deprotected (piperazin-1-yl).

Application: 3-[4-(tertbutoxycarbonyl)piperazin-1-yl]benzoic acid is commonly used in the field of organic synthesis as a precursor of protecting group or intermediate. It can be used as an important intermediate in the synthesis of peptides, drugs and energy materials.

preparation method: usually, 3-[4-(tertbutoxycarbonyl)piperazin-1-yl]benzoic acid can be prepared by reacting piperazine with benzoic acid and removing the protecting group. Specific synthetic methods may vary depending on experimental conditions and requirements.

Safety information: 3-[4-(tertbutoxycarbonyl)piperazin-1-yl]benzoic acid is generally stable and safe under normal operating conditions. However, as an organic compound, it may have certain toxicity, so you should pay attention to safe operation and avoid direct contact with skin and eyes. In addition, the compound also needs to be protected from moisture and high temperatures during storage and transportation. Local safety guidelines and regulations should be followed during handling and disposal.

Last Update：2024-04-09 20:45:29